Details

Autor(en) / Beteiligte

• Esposito, Francesco
• Lim, Chetana
• Lahat, Eylon
• Shwaartz, Chaya
• Eshkenazy, Rony
• Salloum, Chady
• Azoulay, Daniel

Titel

Combined hepatic and portal vein embolization as preparation for major hepatectomy: a systematic review

Ist Teil von

• HPB (Oxford, England), 2019-09, Vol.21 (9), p.1099-1106

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• Some patients remain deemed unsuitable for resection after portal vein embolization (PVE) because of insufficient hypertrophy of the future remnant liver (FRL). Hepatic and portal vein embolization (HPVE) has been shown to induce hypertrophy of the FRL. The aim of this study was to provide a systematic review of the available literature on HPVE as preparation for major hepatectomy. The literature search was performed on online databases. Studies including patients who underwent preoperative HPVE were retrieved for evaluation. Six articles including 68 patients were published between 2003 and 2017. HPVE was performed successfully in all patients with no mortality and morbidity-related procedures. The degree of hypertrophy of the FRL after HPVE ranged from 33% to 63.3%. Surgical resection after preoperative HPVE could be performed in 85.3% of patients, but 14.7% remained unsuitable for resection because of insufficient hypertrophy of the FRL or tumor progression. Posthepatectomy morbidity and mortality rates were 10.3% and 5.1%, respectively. The postoperative liver failure rate was nil. HPVE as a preparation for major hepatectomy appears to be feasible and safe and could increase the resectability of patients initially deemed unsuitable for resection because of absent or insufficient hypertrophy of the FRL after PVE alone.