Details

Autor(en) / Beteiligte

• Liu, Hui
• Zhang, Hua
• Tong, Xiao-Mei

Titel

Clinical features and prognosis of neonates with nonimmune hydrops fetalis

Ist Teil von

• Zhongguo dang dai er ke za zhi, 2019-03, Vol.21 (3), p.253-258

Ort / Verlag

China

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• To study the clinical features, etiology and prognosis of neonates with nonimmune hydrops fetalis (NIHF). A retrospective analysis was performed for the clinical data and outcomes of 23 neonates with NIHF. Of the 23 neonates with NIHF, 18 (78%) were preterm infants and 5 (22%) were full-term infants; 12 (52%) had birth asphyxia (including 5 cases of severe asphyxia). As for the causes of NIHF, 8 neonates (35%) had twin-twin transfusion syndrome (TTTS), 3 (13%) had cardiovascular malformation, 3 (13%) had parvovirus B19 infection, 2 (9%) had congenital chylothorax, 1 (4%) had Turner syndrome, 1 (4%) had Coxsackie virus infection, and 5 (22%) had unknown etiology. Of the 23 neonates, 13 achieved clinical cure, 10 died, resulting in a neonatal mortality rate of 43%. Compared with the survival group, the death group had a significantly higher proportion of preterm infants or infants with asphyxia, 5-minute Apgar score<8 or heart failure (100%/100%/60%/60% vs 62%/15%/8%/8%; P<0.05). Birth asphyxia is common in neo