Details

Autor(en) / Beteiligte

• Ma, Wenli
• Guo, Lihua
• Tian, Zhenzhen
• Zhang, Shumiao
• He, Xiangdong
• Li, JuanJuan
• Yang, Yuliang
• Liu, Zhe

Titel

Rhodamine-modified fluorescent half-sandwich iridium and ruthenium complexes: potential application as bioimaging and anticancer agents

Ist Teil von

• Dalton transactions : an international journal of inorganic chemistry, 2019-04, Vol.48 (15), p.4788-4793

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Most half-sandwich metal anticancer complexes are non-fluorescent, which results in an uncertain mechanism of action (MoA). We designed and synthesized eight fluorescent half-sandwich iridium (Ir) and ruthenium (Ru) complexes by introducing rhodamine derivatives into the N^N-chelating ligand. These complexes have features of bio-imaging and anticancer agents and may merit future development as novel anticancer agents.