Details

Autor(en) / Beteiligte

• Morotti, Andrea
• Busto, Giorgio
• Bernardoni, Andrea
• Tamborino, Carmine
• Fainardi, Enrico

Titel

Association between perihematomal cerebral blood volume and intracerebral hemorrhage expansion: A computed tomography perfusion study

Ist Teil von

• Annals of neurology, 2019-06, Vol.85 (6), p.943-947

Ort / Verlag

Hoboken, USA: John Wiley & Sons, Inc

Erscheinungsjahr

2019

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• We investigated whether computed tomography (CT) perfusion can identify intracerebral hemorrhage patients at high risk of hematoma growth (HG). A total of 155 subjects underwent CT perfusion on admission. Variables associated with log‐transformed absolute HG were explored with multivariable linear regression. Perihematomal cerebral blood volume (CBV) was inversely associated with HG (B = –0.20; p < 0.001), independently from blood pressure, hematoma volume, and other confounders. This association was not dose dependent, and only very low CBV (<1.4 ml/100 g) was significantly associated with HG (B = 0.25; p < 0.001). In conclusion, reduced perihematomal CBV is associated with HG, suggesting a potential role of the perihematomal region in the pathophysiology of hematoma enlargement. ANN NEUROL 2019;85:943–947.