Details

Autor(en) / Beteiligte

• Domínguez-Serrano, F de Borja
• Jiménez-López, E
• Ramos Jiménez, M
• Ponte-Zuñiga, B
• Gómez-Escobar, A
• Díaz-Granda, M J
• Gutiérrez-Sánchez, E
• Morillo-Sánchez, M J
• Menéndez-de-León, C
• Rodríguez-de-la-Rúa-Franch, E

Titel

Importance of ocular electrophysiology in the diagnosis of retinal dystrophies

Ist Teil von

• Archivos de la Sociedad Española de Oftalmología (English ed.), 2019-04, Vol.94 (4), p.160-164

Erscheinungsjahr

2019

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• BACKGROUND AND OBJECTIVEThe diagnosis of retinal dystrophies is complex and is based on complete ophthalmological study, genetic study and electrophysiological studies (EPS). In this study, we intend to evaluate the role of electrophysiological and medical tests in the diagnosis of retinal dystrophies. MATERIAL AND METHODSA retrospective observational study was conducted on 50 selected patients that attended the Neurophysiology Department of the University Hospital Virgen Macarena. An analysis was made of the variables that included, gender, age, referral hospital, reason for which the EPS was requested, applied EPS, genetic study, presumed diagnosis, and definitive diagnosis after EPS. A classification system was subsequently developed, which gives each case a value between 0 and 2, depending on the contribution of the electrophysiological tests to the final diagnosis. RESULTSThe mean age was 44.34 ±18.03 years (60% women). Retinitis pigmentosa (24%), optic neuropathy (12%), and Stargardt's disease (8%) were the most frequent diagnoses. The EPS modified the presumed diagnosis in 48% of the cases, confirmed the diagnosis in 44%, and did not provide any useful information in 8%. The contribution of the EPS was greater in patients seen in the HUVM and when requested by findings in the examination (P=.001). The false positives in the diagnosis of retinal dystrophy were 60% in patients not evaluated by the University Hospital Virgen Macarena. CONCLUSIONSElectrophysiological test and specialised management of patients with retinal dystrophies play an important role in the diagnosis of these conditions.