Details

Autor(en) / Beteiligte

• Xiao, Chun-Hong
• Wan, Jia
• Liu, Hui
• Qiu, Le
• Wang, Fei
• Liu, Sheng
• Lü, Xiong-Wen
• Chen, Xu-Lin

Titel

Red blood cell distribution width is an independent risk factor in the prediction of acute respiratory distress syndrome after severe burns

Ist Teil von

• Burns, 2019-08, Vol.45 (5), p.1158-1163

Ort / Verlag

Netherlands: Elsevier Ltd

Erscheinungsjahr

2019

Link zum Volltext

Quelle

Elsevier ScienceDirect Journals

Beschreibungen/Notizen

• •A blood sample was taken at admission after severe burns and RDW was examined.•Every 1% increase in RDW was associated with a 29% increase in the risk to develop ARDS.•RDW is an independent risk factor in the prediction of ARDS after severe burns. The occurrence of acute respiratory distress syndrome (ARDS) significantly increases the mortality and morbidity of major burns; there are few laboratory markers that predict the development of ARDS in severe burns. This study was to investigate the relationship between complete blood count (CBC) parameters and the incidence of ARDS in severe burn patients. An eight-year retrospective study was performed on 610 severe burn patients who were admitted to the First Affiliated Hospital of Anhui Medical University and Rui Jin Hospital of Shanghai Jiao Tong University from January 2008 to December 2015. The patients were divided into two groups based on the development of ARDS. A blood sample was taken at admission and CBC parameters were examined. Univariate logistic regression analysis was used to evaluate the risk factors for the development of ARDS. Of these 610 patients, 143 developed ARDS giving a rate of 23.44%. The percentage of deep second degree and full thickness burn, inhalation injury and red blood cell distribution width (RDW) were independently associated with the development of ARDS in severe burn patients. Every 1% increase in RDW was associated with a 29% increase in the risk to develop ARDS. The findings of this study suggest that an elevated RDW is associated with an increased risk of ARDS and RDW is an independent risk factor in the prediction of ARDS after severe burns.