Details

Autor(en) / Beteiligte

• Andonov, Anton
• Robbins, Mark
• Borlang, Jamie
• Cao, Jingxin
• Hatchette, Todd
• Stueck, Ashley
• Deschambault, Yvon
• Murnaghan, Kyle
• Varga, Jessy
• Johnston, Lynn

Titel

Rat Hepatitis E Virus Linked to Severe Acute Hepatitis in an Immunocompetent Patient

Ist Teil von

• The Journal of infectious diseases, 2019-08, Vol.220 (6), p.951-955

Ort / Verlag

United States: Oxford University Press

Erscheinungsjahr

2019

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• Hepatitis E virus (HEV) is a major public health concern in developing countries where the primary transmission is via contaminated water. Zoonotic HEV cases have been increasingly described in Europe, Japan, and the United States, with pigs representing the main animal reservoir of infection. We report an unusual acute hepatitis infection in a previously healthy man caused by a rat HEV with a considerably divergent genomic sequence compared with other rat HEV strains. It is possible that rat HEV is an underrecognized cause of hepatitis infection, and further studies are necessary to elucidate its potential risk and mode of transmission.