Details

Autor(en) / Beteiligte

• Yuan, Rong-Xin
• Xiong, Ren-Gen
• Chen, Zhen-Feng
• Zhang, Pei
• Ju, Huang-Xian
• Dai, Zong
• Guo, Zi-Jian
• Fun, Hoong-Kun
• You, Xiao-Zeng

Titel

Crystal structure of zinc(II) 2-sulfanilamidopyrimidine: a widely used topical burn drug

Ist Teil von

• Dalton : an international journal of inorganic chemistry, 2001-01 (6), p.774-776

Erscheinungsjahr

2001

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The reaction of H-SD (sulfadiazine) with Zn(OAc) sub(2) times 2H sub(2)O in water-ethanol was investigated under solvothermal reaction conditions. The reaction yielded crystals of Zn(SD) sub(2) (1) suitable for X-ray analysis and its 1-D polymeric nature was found to be biologically relevant to the slow release of Zn sub(2+) when applied in tropical burn therapy. The results showed that the drug formed a 1-D polymeric chain in which the Zn atom was tightly held by three SD ligands.