Details

Autor(en) / Beteiligte

• Okabe, Hirohisa
• Ohsaki, Takayuki
• Ogawa, Katsuhiro
• Ozaki, Nobuyuki
• Hayashi, Hiromitsu
• Akahoshi, Shinichi
• Ikuta, Yoshiaki
• Ogata, Kenichi
• Baba, Hideo
• Takamori, Hiroshi

Titel

Frailty predicts severe postoperative complications after elective colorectal surgery

Ist Teil von

• The American journal of surgery, 2019-04, Vol.217 (4), p.677-681

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• We aim to clarify if frailty affects severe postoperative complications in elective colorectal surgery. Consecutive 269 colorectal cancer patients older than 65 years undergoing curative surgery were enrolled in this study. The relevance of the frailty and sarcopenia to postoperative outcome was assessed. Clinical frailty (CF) was defined as clinical frailty scale (CFS) ≥ 4. Sarcopenia was assessed by measuring skeletal muscle area using computed tomography. Seventy-eight patients (29%) had CF and 159 patients (59%) had sarcopenia. CF was significantly associated with older age (P = 0.0008), postoperative severe complications (P = 0.001), and postoperative in-hospital stay (P < 0.0001), although sarcopenia was not. Logistic regression analysis revealed that low anterior resection and CF were independent predictors of severe postoperative complications (P = 0.038 and P = 0.001, respectively). CF, but not sarcopenia, is a robust predictor of severe postoperative complications in patients with colorectal cancer. •Frailty assessed by clinical frailty scale is associated with severe postoperative complication for patients undergoing colorectal surgery.•Frailty is of great clinical importance in assessing a risk of elective colorectal surgery.