Details

Autor(en) / Beteiligte

• Trautmann, A
• Götzendorfer, B
• Walther, T
• Hellmann, R

Titel

Scaffolds in a shell-a new approach combining one-photon and two-photon polymerization

Ist Teil von

• Optics express, 2018-11, Vol.26 (23), p.29659-29668

Ort / Verlag

United States

Erscheinungsjahr

2018

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• We report on a laser system combining one-photon and two-photon polymerization for precise and fast fabrication of macroscopic three-dimensional structures featuring microscale and nanoscale characteristics. This single-stage process significantly reduces the production time as demonstrated by scaffolds in a shell application. Porous scaffolds with different pore sizes are surrounded by a ring so that cells can be seeded directly to the scaffolds kept in a shell and do not spread over the whole substrate expecting a saving of cell suspension, faster growth on the scaffolds, and a more controllable environment. Compared to a two-photon polymerization process, the ring is fabricated about 500 times faster using one-photon polymerization. The presented hybrid process qualifies for further applications illustrated by a fluidic system.