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A review of psychiatric conceptions of mental and behavioural disorders in Prader-Willi syndrome
Ist Teil von
Neuroscience and biobehavioral reviews, 2018-12, Vol.95, p.396-405
Ort / Verlag
United States: Elsevier Ltd
Erscheinungsjahr
2018
Link zum Volltext
Quelle
MEDLINE
Beschreibungen/Notizen
•Mental and behavioural disorders in PWS resemble symptoms in psychiatric illnesses.•Are the mental and behavioural deviations in PWS the same as those described for the general population in DSM-V and ICD-10?.•Can we infer similar genetic causes in the general population?.•Implications of high rate of psychosis in disomy genetic subtype.
We present a review of psychiatric associations with comorbid mental and behavioural disorders affecting people with Prader-Willi syndrome (PWS). This literature review suggests that some assumptions about psychiatric associations of PWS behaviours are unjustified (eg skin picking as OCD) and that genetic aetiology should be considered when making associations between PWS mental and behavioural disorders and psychiatric disorders in the general populationThe literature review also demonstrates the limitations of the studies in terms of small numbers, non-representativeness, and lack of replication.