Details

Autor(en) / Beteiligte

• Hsieh, Chia‐Ju
• Su, Wei‐Juin
• Wu, Shiao‐Chi
• Chiu, Jen‐Hwey
• Lin, Li‐Chan

Titel

Efficacy of acupressure to prevent adverse reactions to anti‐tuberculosis drugs: Randomized controlled trials

Ist Teil von

• Journal of advanced nursing, 2019-03, Vol.75 (3), p.640-651

Ort / Verlag

England: Wiley Subscription Services, Inc

Erscheinungsjahr

2019

Quelle

Access via Wiley Online Library

Beschreibungen/Notizen

• Aim To determine whether acupressure can prevent or relieve the adverse drug reactions (ADRs) of anti‐tuberculosis drugs. Background People receiving drug treatment for TB often experience ADRs that may cause them to stop taking their medication. Acupressure is a form of traditional Chinese medicine that can be applied to alleviate or prevent disease symptoms. Design A double‐blinded, repeated‐measures clinical trial in hospitals in Taiwan was carried out from April 2015 – May 2017. Methods Convenience sampling was used to select 32 people (15 for the experimental group and 17 for the control group) aged >20 years who were taking anti‐tuberculosis drugs. The people were randomized to receive 4‐week of true acupressure and 4‐weeks of sham acupressure. Acupressure therapy was given by a researcher in all cases. Both groups received treatment once per day on weekdays, with 15 min for each acupressure session. Outcomes (gastrointestinal irritation and adverse skin reactions) were assessed according to the people feedback and the physicians’ recordings during the treatment course, and during monthly follow‐up visits for 6 months thereafter. Results Both groups typically experienced gastrointestinal irritation and adverse skin reactions within 2 months of beginning anti‐tuberculosis drug treatment. The 4‐weeks intervention involving relevant acupressure points successfully relieved both types of side effects in both immediate and delayed manner. Conclusions When correctly implemented, acupressure can prevent and relieve the ADRs of anti‐tuberculosis drugs, and motivate people to complete their treatment course. 目的 确定穴位按压能否预防或减轻抗结核药物的不良反应。 背景 接受结核病药物治疗的患者经常会出现不良反应,他们可能会因此停药。穴位按压是一种中医治疗方法,可以用来缓解或预防疾病症状。 设计 2015年4月至2017年5月,在台湾的医院进行了一项双盲、重复测量的临床试验。 方法 采用便利抽样原则,共选择了32名患者(实验组15名,对照组17名),患者年龄均大于20岁,并正在服用抗结核药物。随机分配患者接受4周的真实穴位按压或4周的假穴位按压。研究人员对所有患者进行了指压疗法。两组在工作日每天接受一次治疗,每次穴位按压疗程15分钟。治疗过程中,以及随后6个月的每月随访中,根据患者的反馈和医生的记录评估结果(胃肠道刺激和皮肤不良反应)。 结果 两组患者一般在开始抗结核药物疗法后的两个月内出现胃肠道刺激和皮肤不良反应。经过为期4周对相关穴位的按压干预后,这两种副作用分别即时和延迟缓解。 结论 如果实施正确,穴位按压可以预防和减轻抗结核药物疗法的不良反应,并鼓励患者完成的治疗过程。