Details

Autor(en) / Beteiligte

• Zingler, N.
• Weichenrieder, O.
• Schumann, G.G.

Titel

APE-type non-LTR retrotransposons: determinants involved in target site recognition

Ist Teil von

• Cytogenetic and genome research, 2005-01, Vol.110 (1-4), p.250-268

Ort / Verlag

Basel, Switzerland: S. Karger AG

Erscheinungsjahr

2005

Quelle

MEDLINE

Beschreibungen/Notizen

• Non-long terminal repeat (Non-LTR) retrotransposons represent a diverse and widely distributed group of transposable elements and an almost ubiquitous component of eukaryotic genomes that has a major impact on evolution. Their copy number can range from a few to several million and they often make up a significant fraction of the genomes. The members of the dominating subtype of non-LTR retrotransposons code for an endonuclease with homology to apurinic/apyrimidinic endonucleases (APE), and are thus termed APE-type non-LTR retrotransposons. In the last decade both the number of identified non-LTR retrotransposons and our knowledge of biology and evolution of APE-type non-LTR retrotransposons has increased tremendously.