The New England journal of medicine, 2018-10, Vol.379 (15), p.1416-1430
- Grinfeld, Jacob
- Nangalia, Jyoti
- Baxter, E. Joanna
- Wedge, David C
- Angelopoulos, Nicos
- Cantrill, Robert
- Godfrey, Anna L
- Papaemmanuil, Elli
- Gundem, Gunes
- MacLean, Cathy
- Cook, Julia
- O’Neil, Laura
- O’Meara, Sarah
- Teague, Jon W
- Butler, Adam P
- Massie, Charlie E
- Williams, Nicholas
- Nice, Francesca L
- Andersen, Christen L
- Hasselbalch, Hans C
- Guglielmelli, Paola
- McMullin, Mary F
- Vannucchi, Alessandro M
- Harrison, Claire N
- Gerstung, Moritz
- Green, Anthony R
- Campbell, Peter J
2018
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Details
- Autor(en) / Beteiligte
- Grinfeld, Jacob
- Nangalia, Jyoti
- Baxter, E. Joanna
- Wedge, David C
- Angelopoulos, Nicos
- Cantrill, Robert
- Godfrey, Anna L
- Papaemmanuil, Elli
- Gundem, Gunes
- MacLean, Cathy
- Cook, Julia
- O’Neil, Laura
- O’Meara, Sarah
- Teague, Jon W
- Butler, Adam P
- Massie, Charlie E
- Williams, Nicholas
- Nice, Francesca L
- Andersen, Christen L
- Hasselbalch, Hans C
- Guglielmelli, Paola
- McMullin, Mary F
- Vannucchi, Alessandro M
- Harrison, Claire N
- Gerstung, Moritz
- Green, Anthony R
- Campbell, Peter J
- Titel
- Classification and Personalized Prognosis in Myeloproliferative Neoplasms
- Ist Teil von
- The New England journal of medicine, 2018-10, Vol.379 (15), p.1416-1430
- Ort / Verlag
- United States: Massachusetts Medical Society
- Erscheinungsjahr
- 2018
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Genetic analysis involving 2035 patients with a myeloproliferative disorder identified eight genomic subgroups with distinct clinical phenotypes, risk of leukemic transformation, and event-free survival.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0028-4793eISSN: 1533-4406DOI: 10.1056/NEJMoa1716614Titel-ID: cdi_proquest_miscellaneous_2118305324
- Format
- –
- Schlagworte
- Bayes Theorem, Blood cancer, Bone marrow, Calreticulin - genetics, Cancer, Cancer therapies, Classification, Classification schemes, Clinical trials, Diagnosis, Disease Progression, Disease-Free Survival, DNA, Neoplasm - analysis, Exons, Genes, Genetic transformation, Genomes, Genomics, Humans, Janus kinase 2, Janus Kinase 2 - genetics, Laboratories, Leukemia, Medical prognosis, Medical research, Multivariate Analysis, Mutation, Myelofibrosis, Myeloproliferative Disorders - classification, Myeloproliferative Disorders - genetics, Patients, Phenotype, Phenotypes, Polycythemia, Polycythemia vera, Precision Medicine, Prognosis, Proportional Hazards Models, Receptors, Thrombopoietin - genetics, Sequence Analysis, DNA, Stem cells, Tumors