Details

Autor(en) / Beteiligte

• Dellago, H.
• Grillari, J.
• Löscher, Marlies
• Ajuh, P.
• Ritter, G.
• Eisenhaber, F.
• Lamond, A.
• Katinger, H.

Titel

8. hExo70, a subunit of the exocyst complex – a possible link between vesicular transport, pre-mRNA splicing and aging?

Ist Teil von

• Experimental gerontology, 2009-01, Vol.44 (1-2), p.128-128

Ort / Verlag

Elsevier Inc

Erscheinungsjahr

2009

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• The exocyst is a complex consisting of eight subunits and involved in protein targeting to plasma membrane domains. So far only cytoplasmic localization of the exocyst has been reported. We have previously shown that one of its subunits, hExo70, interacts directly with the nuclear splicing factor SNEV, a protein which is implicated in regulation of the replicative life-span of human endothelial cells.