Journal of perinatology, 2019-01, Vol.39 (1), p.80-85
2019
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- Autor(en) / Beteiligte
- Titel
- Urinary tract infection is common in VLBW infants
- Ist Teil von
- Journal of perinatology, 2019-01, Vol.39 (1), p.80-85
- Ort / Verlag
- United States: Nature Publishing Group
- Erscheinungsjahr
- 2019
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Determine the significance of urinary tract infection (UTI) as a cause of late onset sepsis (LOS) in very low birth weight (VLBW) infants in the Neonatal Intensive Care Unit (NICU). Analysis of blood, cerebrospinal fluid and urine culture results in VLBW infants >72-h old, admitted to the Georgetown University Hospital NICU between 2005 and 2015. Of 527 VLBW infants, 297 (56.4%) underwent 911 evaluations for LOS; only one-third included urine cultures. UTI was diagnosed in 8.5% of VLBW infants (range 2-15.9%) and in 13.8% of infants weighing < 1000 g at birth. Gram-negative infections predominated. Concomitant blood cultures were negative in 96% of infants. UTI was more common than bloodstream infection by 2015. UTI is a significant cause of infection in VLBW infants. Urine culture should be included in all LOS evaluations in order to facilitate accurate diagnosis and appropriate antibiotic therapy.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0743-8346eISSN: 1476-5543DOI: 10.1038/s41372-018-0226-4Titel-ID: cdi_proquest_miscellaneous_2103679322
- Format
- –
- Schlagworte
- Anti-Bacterial Agents - administration & dosage, Antibiotics, Birth weight, Blood, Cerebrospinal fluid, Complications and side effects, Demographic aspects, Design analysis, Early Diagnosis, Early Medical Intervention - methods, Early Medical Intervention - standards, Female, Gram-Negative Bacteria - classification, Gram-Negative Bacteria - isolation & purification, Health aspects, Humans, Infant, Newborn, Infant, Very Low Birth Weight - urine, Infants, Infections, Intensive care, Intensive Care Units, Neonatal - statistics & numerical data, Intensive Care, Neonatal - methods, Intensive Care, Neonatal - standards, Low birth weight, Male, Neonatal care, Neonatal Sepsis - epidemiology, Neonatal Sepsis - etiology, Neonatal Sepsis - prevention & control, Neonates, Newborn infants, Pediatric research, Risk factors, Sepsis, Statistics, United States - epidemiology, Urinalysis - methods, Urinalysis - statistics & numerical data, Urinary tract, Urinary tract diseases, Urinary tract infections, Urinary Tract Infections - diagnosis, Urinary Tract Infections - epidemiology, Urinary Tract Infections - microbiology, Urinary Tract Infections - therapy, Urine, Urogenital system, Weight