Details

Autor(en) / Beteiligte

• Deng, Ze-Hui
• Xu, Gui-Ju
• Wang, Xiao-Li
• Wang, Xia
• Wang, Ming-Lin
• Lin, Jin-Ming
• Zhao, Ru-Song

Titel

A Zr(IV)-based porphyrinic metal-organic framework as a solid-phase sorbent for extraction of sulfonamides prior to their quantitation by LC-MS

Ist Teil von

• Mikrochimica acta (1966), 2018-10, Vol.185 (10), p.450-8, Article 450

Ort / Verlag

Vienna: Springer Vienna

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A porphyrinic metal–organic framework (PCN-224) was fabricated and used as an adsorbent for solid-phase extraction of ultratrace levels of polar sulfonamide antibiotics from food and drinking waters. The PCN-224 was characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, and powder X-ray diffraction analyses. Parameters affecting the extraction efficiency were optimized. The sulfonamides were quantified by liquid chromatography-tandem mass spectrometry. Figures of merit include (a) low limits of detection (0.07–0.47 ng·L −1 ), (b) wide linear ranges (0.5–2000 ng·L −1 ), and (c) good repeatabilities (2.8%–6.7%) and reproducibilities (1.7%–5.1%). The method was successfully applied to the determination of sulfonamides in food and drinking water samples. Graphical abstract A Zr(IV)-based porphyrinic metal−organic framework (PCN-224) was synthesized from a Zr 6 cluster and the H 2 TCPP ligand. It was used for solid-phase extraction of sulfonamides from food and drinking water samples coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) for determination.