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Angewandte Chemie International Edition, 2018-11, Vol.57 (45), p.14942-14946
International ed. in English, 2018
Volltextzugriff (PDF)

Details

Autor(en) / Beteiligte
Titel
Immuno‐affinity Amperometric Detection of Bacterial Infections
Ist Teil von
  • Angewandte Chemie International Edition, 2018-11, Vol.57 (45), p.14942-14946
Auflage
International ed. in English
Ort / Verlag
Germany: Wiley Subscription Services, Inc
Erscheinungsjahr
2018
Quelle
Alma/SFX Local Collection
Beschreibungen/Notizen
  • A combination of an immuno‐affinity enrichment strategy and sensitive amperometric read‐out was implemented in a point‐of‐care platform intended for bacterial infection analysis. Bacterial cells, selectively captured and enriched from complex matrices through immuno‐affinity, were detected by amperometric monitoring of the redox state of metabolic activity indicators, providing species identification and viable‐cell quantification. The method was successfully employed for the diagnosis of bacterial infections including antimicrobial susceptibility testing with only several hours of total working time. Sensing resistance: A sensitive immuno‐affinity‐based electrochemical method was proposed for bacterial pathogen identification, quantification, and antimicrobial susceptibility testing through the amperometric monitoring of the redox state of metabolic activity indicators. Using this method, the diagnosis of bacterial infections was accomplished within several hours.
Sprache
Englisch
Identifikatoren
ISSN: 1433-7851
eISSN: 1521-3773
DOI: 10.1002/anie.201808666
Titel-ID: cdi_proquest_miscellaneous_2100331249

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