Details

Autor(en) / Beteiligte

• Camargo, Érica Cristina Sá de
• Massaro, Ayrton Roberto
• Bacheschi, Luiz Alberto
• D’Amico, Élbio Antônio
• Villaça, Paula Ribeiro
• Bassitt, Rogério Pastore
• Gualandro, Sandra Fátima
• Bendit, Israel
• Scaff, Milberto

Titel

Ethnic Differences in Cerebral Venous Thrombosis

Ist Teil von

• Cerebrovascular diseases (Basel, Switzerland), 2005-01, Vol.19 (3), p.147-151

Ort / Verlag

Basel, Switzerland: S. Karger AG

Erscheinungsjahr

2005

Quelle

MEDLINE

Beschreibungen/Notizen

• Background: Cerebral venous thromboses (CVT) with distinct clinical presentations have been shown worldwide. However, there is little information regarding race-ethnic differences in this disease. Methods: We prospectively studied 50 CVT patients from Brazil, comparing clinical and laboratory data among white (W) and African-Brazilian (AB) patients. Results: Seventy percent of the patients were female, 26 W and 23 AB, mean age 34.7 years. Multiple sinus CVT, deep CVT and worse outcome were significantly more frequent in AB than in W patients. There was a trend towards a higher frequency of factor V Leiden and prothrombin mutation in W than in AB, and of protein C deficiency in AB. Conclusions: CVT was more severe in AB patients than in W patients. Race-ethnic differences may account for the heterogeneous distribution of inherited thrombophilia in this series.