Details

Autor(en) / Beteiligte

• Beyer, Peter
• Moorthy, Vasee
• Paulin, Sarah
• Hill, Suzanne R
• Sprenger, Marc
• Garner, Sarah
• Simão, Mariângela
• Guerra, Ranieri
• Magrini, Nicola
• Swaminathan, Soumya

Titel

The drugs don't work: WHO's role in advancing new antibiotics

Ist Teil von

• The Lancet (British edition), 2018-07, Vol.392 (10144), p.264-266

Ort / Verlag

England: Elsevier Ltd

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• The increasing emergence and spread of antimicrobial resistance is jeopardising the effectiveness of existing antibiotics.1 Since the golden age of antibiotic discovery in the 1950s and 1960s, few innovative antibiotics have been developed due to the scientific challenges and limited investment.2 Increasing antimicrobial resistance globally and inadequate development of new antibacterial treatments are threatening the achievement of universal health coverage (UHC) and the Sustainable Development Goals (SDGs).3 There have been intense discussions on these issues at the UN General Assembly, the World Health Assembly, the G7, the G20, the World Economic Forum, and other venues. [...]as part of the blueprint, WHO is systematically drafting research and development roadmaps using a standardised methodology to identify critical research and product development needs. All these activities will form part of the future Global Development and Stewardship Framework to combat antimicrobial resistance that WHO, the Food and Agriculture Organization of the United Nations, and the World Organisation for Animal Health (OIE) are developing in line with the mandate provided by the UN High Level Declaration on Antimicrobial Resistance.12 This work will also inform work of the Ad-Hoc Interagency Coordination Group on Antimicrobial Resistance which will report back to the UN General Assembly in 2019 on how to ensure sustained effective global action to address antimicrobial resistance.