Details

Autor(en) / Beteiligte

• Cashman, Kevin D.
• Ritz, Christian
• Adebayo, Folasade A.
• Dowling, Kirsten G.
• Itkonen, Suvi T.
• Öhman, Taina
• Skaffari, Essi
• Saarnio, Elisa M.
• Kiely, Mairead
• Lamberg-Allardt, Christel

Titel

Differences in the dietary requirement for vitamin D among Caucasian and East African women at Northern latitude

Ist Teil von

• European journal of nutrition, 2019-09, Vol.58 (6), p.2281-2291

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• Context Current vitamin D recommendations have been established based on an assumption that there are no differences between Caucasian and other ethnic/racial groups in terms of vitamin D requirements. This assumption, largely made due to the absence of data, is a key knowledge gap identified by a number of authorities. Objective To test whether the distribution of dietary requirements for maintaining winter serum 25-hydroxyvitamin D [25(OH)D] concentrations ≥ 30 nmol/L (a priority threshold linked to vitamin D deficiency prevention) differ between Caucasian and Somali women living at northerly latitude. Methods We used data from a 5-month, winter-based, vitamin D 3 dose-related randomized, placebo-controlled trial in Somali ( n 47) and Causcian women ( n 69), aged 21–64-year old, living in Southern Finland (60°N), to model the vitamin D intake–serum 25(OH)D dose–response relationship. Regression analyses were used to predict the vitamin D intake required to maintain 97.5% (as well as 50, 90, and 95%) of women in both ethnic groups above serum 25(OH)D thresholds of 30, 40 and 50 nmol/L. Results Using a model which adjusted for baseline 25(OH)D, age, and BMI, the estimated vitamin D intake that maintained serum 25(OH)D ≥ 30 nmol/L in 97.5% of Caucasian and Somali women was 8 and 18 µg/day, respectively. Ethnic differences were also evident at 40 and 50 nmol/L serum 25(OH)D thresholds. Conclusion The present study adds further evidence that ethnic differences in the dietary requirement for vitamin D do exist and that dose–response vitamin D intervention studies are required in at-risk target populations specified by ethnicity.