Details

Autor(en) / Beteiligte

• Cui, Peng-Fei
• Zhuang, Wan-Ru
• Hu, Xi
• Xing, Lei
• Yu, Ru-Yi
• Qiao, Jian-Bin
• He, Yu-Jing
• Li, Fangyuan
• Ling, Daishun
• Jiang, Hu-Lin

Titel

A new strategy for hydrophobic drug delivery using a hydrophilic polymer equipped with stacking units

Ist Teil von

• Chemical communications (Cambridge, England), 2018, Vol.54 (59), p.8218-8221

Ort / Verlag

England: Royal Society of Chemistry

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A highly hydrophilic polymer equipped with guanidinium groups was used to load aromatic ring-containing hydrophobic agent doxorubicin (DOX) via π-π interaction. The results have shown that the delivery system exhibited enhanced cellular uptake and antitumor efficiency compared with free drugs. This study opens new avenues for the application of hydrophilic polymers in drug delivery.