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British journal of neurosurgery, 2000-10, Vol.14 (5), p.415-422
Ort / Verlag
England: Informa UK Ltd
Erscheinungsjahr
2000
Quelle
Taylor & Francis Journals Auto-Holdings Collection
Beschreibungen/Notizen
After providing an overview of depression this article briefly reviews the development of psychosurgery and outlines the current procedures in use world wide. Stereotactic subcaudate tractotomy (SST) is described in particular detail, and the rationale for its use in the treatment of resistant depression is then discussed by considering the findings of neuropsychological, neurophysiological and neuroimaging studies. The emerging evidence suggests that the prefrontal cortex subserves an essential function in emotion and that disruption of its connections modifies mood.