Details

Autor(en) / Beteiligte

• Divgi, Chaitanya

Titel

The Current State of Radiopharmaceutical Therapy

Ist Teil von

• Journal of Nuclear Medicine, 2018-11, Vol.59 (11), p.1706-1707

Ort / Verlag

United States: Society of Nuclear Medicine

Erscheinungsjahr

2018

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Divgi comments about Edward Coleman at Duke University led the systematic evaluation of I-meta-iodo-benzylguanidine (l-MIBG) therapy in adult NET, and an article by Kane et al. The retrospective review by Kane et al. demonstrated significant symptom relief and survival benefit in 211 patients treated with l-MIBG for metastatic neuroendocrine tumors at Duke University Hospital from 1991 to 2014. The review confirms what the community has known for quite a while: l-MIBG therapy results in symptom improvement, and a delay in tumor growth, in a substantial proportion of treated patients. As nuclear medicine physicians, they have 2 broad clinical responsibilities. They evaluate images of in vivo radiopharmaceutical distribution to make clinical decisions, and they treat patients with therapeutic radiopharmaceuticals, bringing to bear their understanding of (molecular and clinical) radiochemistry, biology, and pathophysiology.