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Background
The impact of total minimally invasive esophagectomy (MIE) on early postoperative outcome and patient’s survival is a matter of recent discussion.
Methods
We performed a 1:2 propensity score-matched comparison of 20 patients who underwent 3D-MIE and high intrathoracic esophagogastrostomy with 40 patients who underwent hybrid esophagectomy (HYBRID) with laparoscopic gastric mobilization and open transthoracic esophagectomy and the same anastomosis for esophageal adenocarcinoma in 2014 and 2015. Matching criteria were tumor localization, age, gender, and neoadjuvant treatment.
Results
Both groups did not differ regarding overall postoperative complications (MIE 55% vs. HYBRID 50%,
p
= 0.715) and anastomotic leakage (MIE 15% vs. HYBRID 5%,
p
= 0.186). A significant difference was seen regarding the rate of postoperative pneumonia (MIE 5% vs. HYBRID 27.5%;
p
= 0.040) and the postoperative ICU stay (MIE median 1 day vs. HYBRID median 2 days,
p
< 0.001). The R0-resection rate was 100% in both groups and median number of dissected lymph nodes was 32 for MIE and 35 for HYBRID (
p
= 0.236). Significant differences between both groups were noticed for postoperative number of patients with use of opiate demand medication and numeric rating scale for pain (NRSP maximum pain, median) both in favor of the MIE group (MIE 25%, NRSP 2 vs. HYBRID 60%, NRSP 4;
p
= 0.011,
p
< 0.001). Overall 2-year survival rate was 85% in both groups.
Conclusion
Total minimally invasive esophagectomy is superior to hybrid esophagectomy in regard of postoperative pain and rate of pneumonia. No differences exist for postoperative surgical complications or short-term prognosis.