Details

Autor(en) / Beteiligte

• Tretiakova, D.S.
• Alekseeva, A.S.
• Galimzyanov, T.R.
• Boldyrev, A.M.
• Chernyadyev, A.Yu
• Ermakov, Yu.A.
• Batishchev, O.V.
• Vodovozova, E.L.
• Boldyrev, I.A.

Titel

Lateral stress profile and fluorescent lipid probes. FRET pair of probes that introduces minimal distortions into lipid packing

Ist Teil von

• Biochimica et biophysica acta. Biomembranes, 2018-11, Vol.1860 (11), p.2337-2347

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The modern theory of lipid membrane structure incorporates the concept of lateral stress profile. The latter represents the forces that act on any solute inside the membrane. We used this concept to propose two lipid probes that introduce minimal distortions into the lipid bilayer packing: the surface pressure isotherms and volt-potentials of the pure and mixed (probe-containing) lipid monolayers are equal. The probes represent a FRET pair. They are applicable in lipid transfer and vesicle fusion experiments. [Display omitted] •Lateral stress profile is used to predict probes distribution in the bilayer.•FRET pair of probes with very similar structures and distributions is proposed.•The probes introduce minimal distortions into the lipid packing.