Details

Autor(en) / Beteiligte

• Kirkman, Matthew A.
• Pickles, Jessica C.
• Fairchild, Amy R.
• Avery, Aimee
• Pietsch, Torsten
• Jacques, Thomas S.
• Aquilina, Kristian

Titel

Early Wound Site Seeding in a Patient with Central Nervous System High-Grade Neuroepithelial Tumor with BCOR Alteration

Ist Teil von

• World neurosurgery, 2018-08, Vol.116, p.279-284

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• Advances in molecular profiling have facilitated the emergence of newly defined entities of central nervous system (CNS) tumor, including CNS high-grade neuroepithelial tumor with BCOR alteration (CNS HGNET-BCOR). Relatively little is known about the clinical behavior of these newly characterized tumors. We describe a pediatric male patient with CNS HGNET-BCOR, who developed seeding of the tumor into the site of the surgical wound within months of surgery and who underwent resection of a residual posterior fossa tumor. This case emphasizes 3 important points. First, CNS HGNET-BCOR can be aggressive tumors that necessitate close clinical and radiologic surveillance. Second, surveillance imaging in such cases should incorporate the surgical incision site into the field of view, and this should be closely scrutinized to ensure the timely detection of wound site seeding. Third, wound site seeding may still occur despite the use of meticulous surgical techniques. •Central nervous system high-grade neuroepithelial tumors with BCOR alteration can be aggressive tumors.•They necessitate close clinical and radiologic surveillance.•Postoperative imaging should incorporate the incision site into the field of view.•Wound site seeding may still occur despite meticulous surgical techniques.