Details

Autor(en) / Beteiligte

• Sanchez‐Moreno, J.
• Bonnin, C. M.
• González‐Pinto, A.
• Amann, B. L.
• Solé, B.
• Balanzá‐Martinez, V.
• Arango, C.
• Jiménez, E.
• Tabarés‐Seisdedos, R.
• Garcia‐Portilla, M. P.
• Ibáñez, A.
• Crespo, J. M.
• Ayuso‐Mateos, J. L.
• Martinez‐Aran, A.
• Torrent, C.
• Vieta, E.
• Alegría, Analucía
• Al‐Halabi, Susana
• Alonso‐Lana, Silvia
• Anaya, Celia
• López, Purificación
• Bobes, Julio
• Chiclana, Guadalupe
• Cerrillo, Esther
• Correa, Patricia
• Custal, Núria
• Fernández, Patricia
• García, Sainza
• Fuentes‐Durá, Inmaculada
• Galván, Gonzalo
• González‐Ortega, Itxaso
• Isella, Sandra
• Landín‐Romero, Ramon
• Menchón, Manuel
• Merchan‐Naranjo, Jessica
• Ortiz‐Gil, Jordi
• Pacchiarotti, Isabella
• Reyes, Raquel
• Rapado‐Castro, Marta
• Reinares, Maria
• Rodao, Maria
• Saiz, Pilar A
• Segura, Bárbara
• Selva‐Vera, Gabriel
• Saiz‐Ruiz, Jerónimo
• Soria, Virginia
• Zorrilla, Iñaki
• Valle, Jesús
• Valls, Elia
• Varo, Cristina

Titel

Factors associated with poor functional outcome in bipolar disorder: sociodemographic, clinical, and neurocognitive variables

Ist Teil von

• Acta psychiatrica Scandinavica, 2018-08, Vol.138 (2), p.145-154

Ort / Verlag

United States: Blackwell Publishing Ltd

Erscheinungsjahr

2018

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Objective The current investigation aimed at studying the sociodemographic, clinical, and neuropsychological variables related to functional outcome in a sample of euthymic patients with bipolar disorder(BD) presenting moderate‐severe levels of functional impairment. Methods Two‐hundred and thirty‐nine participants with BD disorders and with Functioning Assessment Short Test(FAST) scores equal or above 18 were administered a clinical and diagnostic interview, and the administration of mood measure scales and a comprehensive neuropsychological battery. Analyses involved preliminary Pearson bivariate correlations to identify sociodemographic and clinical variables associated with the FAST total score. Regarding neuropsychological variables, a principal component analysis (PCA) was performed to group the variables in orthogonal factors. Finally, a hierarchical multiple regression was run. Results The best fitting model for the variables associated with functioning was a linear combination of gender, age, estimated IQ, Hamilton Depression Rating Scale (HAM‐D), number of previous manic episodes, Factor 1 and Factor 2 extracted from the PCA. The model, including all these previous variables, explained up to 29.4% of the observed variance. Conclusions Male gender, older age, lower premorbid IQ, subdepressive symptoms, higher number of manic episodes, and lower performance in verbal memory, working memory, verbal fluency, and processing speed were associated with lower functioning in patients with BD.