Trends in endocrinology and metabolism, 2018-09, Vol.29 (9), p.599-602
2018
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Details
- Autor(en) / Beteiligte
- Titel
- Fine-Tuning Mitochondrial Dysfunction and Reductive Carboxylation
- Ist Teil von
- Trends in endocrinology and metabolism, 2018-09, Vol.29 (9), p.599-602
- Ort / Verlag
- United States: Elsevier Ltd
- Erscheinungsjahr
- 2018
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Metabolic processes within cells are dynamically interconnected. If mitochondria become defective, cells must rewire their metabolism to survive. Here we highlight recent work by Gaude et al. that used a tunable model of mitochondrial dysfunction combined with metabolic tracing and in silico analyses to define these compensatory pathways.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1043-2760eISSN: 1879-3061DOI: 10.1016/j.tem.2018.04.002Titel-ID: cdi_proquest_miscellaneous_2030938135
- Format
- –
- Schlagworte
- GAPDH, Glutamine, Glycolysis, MDH1, Mitochondria, NAD, NAD/NADH, Oxidation-Reduction, redox