Details

Autor(en) / Beteiligte

• Sarfati, Céline
• Moore, Alex
• Pilorge, Catherine
• Amaru, Priscilla
• Mendialdua, Paula
• Rodet, Emilie
• Stéphan, François
• Rezaiguia-Delclaux, Saïda

Titel

Efficacy of early passive tilting in minimizing ICU-acquired weakness: A randomized controlled trial

Ist Teil von

• Journal of critical care, 2018-08, Vol.46, p.37-43

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2018

Quelle

ScienceDirect

Beschreibungen/Notizen

• To investigate whether passive tilting added to a standardized rehabilitation therapy improved strength at Intensive Care Unit (ICU) discharge. This single-center trial included patients admitted to an adult surgical ICU and ventilated for at least 3days. Patients were randomized to daily standardized rehabilitation therapy alone or with tilting on a table for at least 1h. The primary outcome was the Medical Research Council (MRC) sum score at ICU discharge. Muscular recovery was a secondary outcome. Of 145 included patients, 125 received mobilization, 65 in the Tilt group and 60 in the Control group. Total mobilization duration (median [25th–75th percentiles]) in the Tilt group was 1020 [580–1695] versus 1340 [536–2775] minutes in the Control group (p=0.313). MRC sum scores at ICU discharge were not significantly different between groups (Tilt, 50 [45–56] versus 48 [45–54]; p=0.555). However, the number of patients with weakness was higher in the Tilt group at baseline (Tilt: 60/65 versus 48/60, p=0.045) and muscular recovery was better in the Tilt group (p=0.004). Passive tilting added to a standardized rehabilitation therapy did not improve muscle strength at ICU discharge in surgical patients even if a faster recovery with tilting is suggested. NCT02047617. •Tilting intensive care unit patients has been advocated to minimize acute weakness•Passive tilting plus early physiotherapy was compared to physiotherapy alone•Tilting added to early physiotherapy affords a faster recovery of muscle weakness