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Background:
Natalizumab (NTZ) is a monoclonal antibody with an immunosuppressive effect that reduces the inflammation of the central nervous system, and it has been used for the treatment of relapsing-remitting multiple sclerosis (RRMS). In patients with low cellular immune response, systemic mycosis arising from endemic areas may occur.
Results and Conclusion:
In this article, we will describe a case of paracoccidioidomycosis as a complication to treatment with NTZ in an RRMS patient.