Details

Autor(en) / Beteiligte

• Dell'Era, Gabriele
• Vecchi, Federica
• Prenna, Eleonora
• Devecchi, Chiara
• Degiovanni, Anna
• Malacrida, Maurizio
• Magnani, Andrea
• Occhetta, Eraldo
• Marino, Paolo

Titel

Feasibility of cathodic‐anodal left ventricular stimulation for alternative multisite pacing

Ist Teil von

• Pacing and clinical electrophysiology, 2018-06, Vol.41 (6), p.597-602

Ort / Verlag

United States: Wiley Subscription Services, Inc

Erscheinungsjahr

2018

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Background Simultaneous cathodic‐anodal capture by a bipole of a cardiac resynchronization therapy (CRT) left‐ventricular (LV) catheter may depolarize a larger LV area than conventional multipoint pacing. We evaluated the feasibility of cathodic‐anodal LV stimulation. Methods In 30 patients undergoing CRT with a quadripolar LV lead, we evaluated the cathodic and anodal capture threshold for each LV pole and compared QRS on electrocardiogram (ECG) during single‐point cathodic biventricular stimulation (S‐BS), multipoint BS (M‐BS), and cathodic‐anodal BS (CA‐BS). Results Anodal capture was obtained by three poles in 23/30 patients, by two poles in five, and was not feasible in two. The mean single‐point anodal threshold was 3.93 V versus single‐point cathodic threshold of 1.95 V. On comparing ECGs, M‐BS and CA‐BS produced similar QRS wavefront activation in 90% of patients. Conclusions CA‐BS is feasible and may be used in LV pacing to achieve a different wavefront of electrical activation. Further prospective studies are needed in order to verify the clinical impact of this kind of stimulation.