Details

Autor(en) / Beteiligte

• Liu, Yu‐Feng
• Zhai, Dan‐Dan
• Zhang, Xiang‐Yu
• Guan, Bing‐Tao

Titel

Potassium‐Zincate‐Catalyzed Benzylic C−H Bond Addition of Diarylmethanes to Styrenes

Ist Teil von

• Angewandte Chemie International Edition, 2018-07, Vol.57 (27), p.8245-8249

Auflage

International ed. in English

Ort / Verlag

Germany: Wiley Subscription Services, Inc

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Direct functionalization of the benzylic C−H bond of diarylmethanes is an important strategy for the synthesis of diarylmethine‐containing compounds. However, the methods developed to date for this purpose require a stoichiometric amount (usually more) of either a strong base or an oxidant. Reported here is the first catalytic benzylic C−H bond addition of diarylmethanes to styrenes and conjugated dienes. A potassium zincate complex, generated from potassium benzyl and zinc amide, acts as a catalyst and displays good activity and chemoselectivity. Considering the atom economy of the reaction and the ready availability of the catalyst, this reaction constitutes a practical, efficient method for diarylalkane synthesis. ‘Zinc' into it: The catalytic addition of the benzylic carbon center of diarylmethanes to styrenes and conjugated dienes was achieved for the first time by using a potassium zincate catalyst. The reaction demonstrates wide scope and high yields.