Details

Autor(en) / Beteiligte

• Hu, Anhua
• Guo, Jing-Jing
• Pan, Hui
• Tang, Haoming
• Gao, Zhaobo
• Zuo, Zhiwei

Titel

δ‑Selective Functionalization of Alkanols Enabled by Visible-Light-Induced Ligand-to-Metal Charge Transfer

Ist Teil von

• Journal of the American Chemical Society, 2018-02, Vol.140 (5), p.1612-1616

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2018

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• We demonstrate the application of ligand-to-metal charge transfer (LMCT) excitation to the direct catalytic generation of energetically challenging alkoxy radicals from alcohols through a coordination–LMCT–homolysis process with an abundant and inexpensive cerium salt as the catalyst. This catalytic manifold provides a simple and efficient way to utilize the characteristic reactivity and selectivity of transient alkoxy radicals for δ-selective C–H bond functionalization. Under mild redox-neutral conditions without the need for prefunctionalization, this method provides a versatile platform to access molecular complexity from simple and abundant alcohols.