Details

Autor(en) / Beteiligte

• Liu, Chung-Hsiang
• Huang, Pai-Hao
• Lien, Li-Ming
• Tsai, I-Ju
• Sung, Fung-Chang
• Hsu, Chung Y.
• Tsai, Chon-Haw
• Tseng, Chun-Hung
• Yang, Yu-Wan
• Cho, Der-Yang
• Chen, Chun-Chung
• Tang, Sung-Chun
• Yeh, Shin-Joe
• Chen, Chih-Hao
• Chen, Han-Jung
• Lu, Kan
• Hsu, Shih-Pin
• Wang, Kuo-Wei
• Chen, Chih-Hung
• Sung, Pi-Shan
• Chiu, Hou-Chang
• Bai, Chyi-Huey
• Lau, Chi-Ieong
• Yeh, Hsu-Ling
• Yen, Cheng-Chang
• Lin, Ruey-Tay
• Huang, Poyin
• Chang, Chia-Yu
• Lin, Kao-Chang
• Cheng, Tain-Junn
• Yang, Chun-Ming
• Lu, Tsong-Ming
• Kung, Sheng-Ling
• Chang, Wei-Lun
• Hsu, Min-Hsien
• Denq, Jong-Chyou
• Sun, Yu
• Lu, Chien-Jung
• Lin, Cheng-Huai
• Huang, Chieh-Cheng
• Chan, Hoi-Fong
• Lee, Siu-Pak
• Sun, Ming-Hui
• Ong, Cheung-Ter
• Su, Yu-Hsiang
• Lin, Jiann-Chyun
• Peng, Giia-Sheun
• Hsu, Chang-Hung
• Yen, Che-Hung
• Liu, Chia-Chen
• Lai, Yu- Hua
• Tsai, Chia-Kuang
• Chiang, Tsuey-Ru
• Sun, Mu-Chien
• Hsiao, Pi-Ju
• Chen, Ta-Cheng
• Lin, Shinn-Kuang
• Yang, Fu-Yi
• Liu, Chih-Yang
• Chang, Chun-Yuan
• Chang, Yang-Chuang
• Fang, Chen-Wen
• Lee, Kuo-Ying
• Li, Chen-Hua
• Hsieh, Chuan-Fa
• Yang, Chih-Dong
• Liao, How-Chin
• Yeh, Shoou-Jeng
• Wu, Ling-Li
• Chen, Chung-Wen
• Hsu, Chih-Shan
• Pan, Yan-Hong
• Chen, Chin-I.
• Sung, Jia-Ying
• Yu, Jia-Ming
• Ho, Chun-Sum
• Lin, Ting-Chun
• Yu, Shih-Chieh
• Chen, Jiunn-Rong
• Wei, Cheng-Yu
• Lee, Chia Fang
• Yang, Sheng-Kung
• Chen, Chih-Lin
• Tseng, Hung-Pin
• Lin, Chun-Jen
• Wang, Shuu-Jiun
• Wong, Wen-Jang
• Tsai, Ching-Piao
• Kwan, Shang-Yeong
• Lee, Yi-Chung
• Huang, Hui-Chi
• Chen, Chao-Ching
• Liu, Yi-Chien
• Chu, Ching-Hua
• Lin, Yi-Chun
• Chou, Ping-Chen
• Chiu, Yi-Pin
• Tsai, Kun-Chang
• Liao, Yi-Sheng

Titel

Renal function is associated with 1-month and 1-year mortality in patients with ischemic stroke

Ist Teil von

• Atherosclerosis, 2018-02, Vol.269, p.288-293

Ort / Verlag

Ireland: Elsevier B.V

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• Renal dysfunction is a potent risk factor for cardiovascular diseases, including stroke. This study aimed to evaluate the impact of admission estimated glomerular filtration rate (eGFR) levels on short-term (1-month) and long-term (1-year) mortality in patients with acute ischemic stroke. From the Taiwan Stroke Registry data, we classified ischemic stroke patients, identified from April 2006 to December 2015, into 5 groups by eGFR at admission: ≥ 90, 60–89, 30–59, 15–29, and <15 mL/min/1.73 m2 or on dialysis. Risks of 1-month mortality and 1-year mortality after ischemic stroke were investigated by the eGFR level. Among 52,732 ischemic stroke patients, 1480 died within one month. The 1-month mortality rate was over 5-fold greater in patients with eGFR <15 mL/min/1.73 m2 or dialysis than in patients with eGFR ≥90 mL/min/1.73 m2 (2.88 versus 0.56 per 1000 person-days). The adjusted hazard ratio (HR) of 1-month mortality increased from 1.31 (95% CI = 1.08–1.59) for patients with eGFR 60–89 mL/min/1.73 m2 to 2.33 (95% CI = 1.80–3.02) for patients with eGFR < 15 mL/min/1.73 m2 or on dialysis. 3226 patients died within one year. The adjusted HR of mortality increased from 1.38 (95% CI = 1.21–1.59) for patients with eGFR 60–89 mL/min/1.73 m2 to 2.60 (95% CI 2.18–3.10) for patients with eGFR < 15 mL/min/1.73 m2 or on dialysis, compared to patients with eGFR ≥ 90 mL/min/1.73 m2. After acute ischemic stroke, patients with reduced eGFR are at elevated risks of short-term and long-term deaths in a graded relationship. •This study aims to evaluate the short-term (1-month) and long-term (1-year) mortality for patients with acute ischemic stroke by the glomerular filtration rate (eGFR) levels measured at admission: ≥ 90, 60–89, 30–59, 15–29, and <15 mL/min/1.73 m2 or on dialysis.•Patients with reduced eGFR were at higher risk of dying either at short- or long-term in a graded relationship.