Details

Autor(en) / Beteiligte

• Yang, Xianwei
• Lei, Chuanfen
• Qiu, Yiwen
• Shen, Shu
• Lu, Changli
• Yan, Lunan
• Wang, Wentao

Titel

Selecting a suitable surgical treatment for hepatic angiomyolipoma: a retrospective analysis of 92 cases

Ist Teil von

• ANZ journal of surgery, 2018-09, Vol.88 (9), p.E664-E669

Ort / Verlag

Melbourne: John Wiley & Sons Australia, Ltd

Erscheinungsjahr

2018

Quelle

Wiley Online Library

Beschreibungen/Notizen

• Background Hepatic angiomyolipoma (HAML) is a rare and difficult‐to‐diagnose liver tumour. The aim of this study was to summarize experiences in the management of HAML and to recommend a practical treatment strategy. Methods We retrospectively studied 92 patients who were diagnosed with HAML and analysed the clinical presentation, histopathological features and treatment of the tumours encountered at our institute from May 2009 to June 2016. Results The patients included 67 females and 25 males who underwent at least one radiographic examination. Sixty‐eight patients underwent radical hepatectomy, two patients underwent liver biopsy, and 22 patients were treated with radiofrequency ablation after liver biopsy. The tumour cells correspondingly expressed both melanoma cell markers (HMB45, MART‐1) and smooth muscle cell markers. Two patients were found to have tumour recurrence (2/92, 2.2%) after radical hepatectomy, and none of the patients died. Conclusion Diagnosis of HAML depends on pathological findings. The treatment strategy for HAML should be selected according to the tumour size, liver biopsy, location and clinical symptoms of HAML. Patients should be followed closely after surgery because of the malignant potential of HAML.