Details

Autor(en) / Beteiligte

• Longo, Dan L
• DeVita, Vincent T

Titel

Progress in the Treatment of Hodgkin’s Lymphoma

Ist Teil von

• The New England journal of medicine, 2018-01, Vol.378 (4), p.392-394

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2018

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• Although there has been considerable research activity in the treatment of Hodgkin’s lymphoma since advanced stages of the disease became curable with combination chemotherapy in the 1960s, the most significant advances have involved the maintenance of a particular level of antitumor efficacy while acute and late toxic side effects and their attendant mortality are reduced. These advances include the preservation of high response rates at reduced levels of toxicity with the current standard regimen of doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD); the demonstration that various forms of radiation therapy were associated with unacceptably high levels of long-term toxicity; the application . . .