Details

Autor(en) / Beteiligte

• Tang, T-Y. Dora
• Cecchi, Dario
• Fracasso, Giorgio
• Accardi, Davide
• Coutable-Pennarun, Angelique
• Mansy, Sheref S
• Perriman, Adam W
• Anderson, J. L. Ross
• Mann, Stephen

Titel

Gene-Mediated Chemical Communication in Synthetic Protocell Communities

Ist Teil von

• ACS synthetic biology, 2018-02, Vol.7 (2), p.339-346

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2018

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A gene-directed chemical communication pathway between synthetic protocell signaling transmitters (lipid vesicles) and receivers (proteinosomes) was designed, built and tested using a bottom-up modular approach comprising small molecule transcriptional control, cell-free gene expression, porin-directed efflux, substrate signaling, and enzyme cascade-mediated processing.