Details

Autor(en) / Beteiligte

• Solla, Paolo
• Cannas, Antonino
• Congia, Socrate
• Floris, Gianluca
• Aste, Rosa
• Tacconi, Paolo
• Marrosu, Maria Giovanna

Titel

Levodopa/carbidopa/entacapone-induced acute Pisa syndrome in a Parkinson’s disease patient

Ist Teil von

• Journal of the neurological sciences, 2008-12, Vol.275 (1), p.154-156

Ort / Verlag

Amsterdam: Elsevier B.V

Erscheinungsjahr

2008

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Abstract Pisa syndrome (PS) is a dystonic lateroflexion of the trunk with a postural disturbance resembling the leaning tower of Pisa. Initially reported as a side effect related to antipsychotic therapy, this original dystonic posture is also manifested in neurodegenerative disorders such as Alzheimer’s disease and multiple system atrophy, or in rare idiopathic cases. Recent observations have described the onset of PS with subchronic course in patients affected by Parkinson’s disease (PD). Here, we report on the acute development of PS in a parkinsonian patient during treatment with entacapone/levodopa/carbidopa combination. This case illustrates how, in contrast to previously well-known chronic/subchronic forms, this axial dystonic posture may occur in PD as an acute onset reversible type, related to levodopa treatment.