Details

Autor(en) / Beteiligte

• Balash, Yacov
• Merims, Doron
• Giladi, Nir

Titel

Suicidal thoughts in patients with Parkinson’s disease treated by deep brain stimulation of the subthalamic nuclei: two case reports and review of the literature

Ist Teil von

• Acta neuropsychiatrica, 2007-06, Vol.19 (3), p.208-210

Ort / Verlag

Cambridge, UK: Cambridge University Press

Erscheinungsjahr

2007

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Background:  Deep brain stimulation (DBS) of the subthalamic nuclei (STN) can result in depression despite the obvious motor improvement. Case presentations:  Two patients with serious life‐threatening depressive episodes are described. In the first case, the trigger for depression was a slight adjustment of the left stimulating electrode’s contact. In the second case, reducing both the dopaminergic therapy and the voltage of DBS resulted in the manifestation of depressive symptoms. Conclusions:  DBS‐induced depression possibly has pathogenetic differences from ordinary Parkinson’s disease depression. The STN region seems to be a sensitive zone that influences emotions.