Details

Autor(en) / Beteiligte

• Qi, Min
• Zhou, Qiuhong
• Zeng, Weiqi
• Wu, Lisha
• Zhao, Shuang
• Chen, Wangqing
• Luo, Chang
• Shen, Minxue
• Zhang, Jianglin
• Tang, Can-E

Titel

Growth factors in the pathogenesis of diabetic foot ulcers

Ist Teil von

• Frontiers in bioscience, 2018-01, Vol.23 (2), p.310-317, Article 4593

Ort / Verlag

Singapore

Erscheinungsjahr

2018

Quelle

MEDLINE

Beschreibungen/Notizen

• Foot ulcers affect 15% of patients with diabetes, resulting in a great health burden. The occurrence and development of diabetic foot ulcers is associated with neuropathy, peripheral arterial disease, and infection. Several growth factors are involved in these processes, including epidermal growth factor, vascular endothelial growth factor, transforming growth factor-beta, fibroblast growth factor, and erythropoietin, which could promote wound healing of patients with diabetes. Thus, this review discusses the role of these growth factors in the pathogenesis of diabetic foot ulcers, aiming to achieve novel insights into the management of diabetic foot ulcers.