Details

Autor(en) / Beteiligte

• Shah, Ami G.
• Peahota, Michelle
• Thoma, Brandi N.
• Kraft, Walter K.

Titel

Medication Complications in Extracorporeal Membrane Oxygenation

Ist Teil von

• Critical care clinics, 2017-10, Vol.33 (4), p.897-920

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics. These changes can lead to exposure-driven decreases in efficacy or increased incidence of side effects. The pharmacokinetic changes are drug specific and largely undefined for most drugs. We review available drug dosing data and provide guidance for use in the ECMO patient population.