Details

Autor(en) / Beteiligte

• Camara-Lemarroy, Carlos R.
• Hoyos, Mariana
• Ibarra-Yruegas, Beatriz E.
• Díaz-Torres, Marco A.
• De León, Rolando

Titel

Affective symptoms and determinants of health-related quality of life in Mexican people with epilepsy

Ist Teil von

• Neurological sciences, 2017-10, Vol.38 (10), p.1829-1834

Ort / Verlag

Milan: Springer Milan

Erscheinungsjahr

2017

Quelle

Psychology and Behavioral Sciences Collection

Beschreibungen/Notizen

• Epilepsy is known to be associated with multiple psychiatric comorbidities, such as depression, sleep-disorders, and anxiety. The objective of this study was to determine the prevalence and impact of affective symptoms over health-related quality of life (QOL) in Mexican people with epilepsy (PWE). We performed a cross-sectional observational study on 73 consecutive PWE and corresponding age- and sex-matched controls. HrQOL was assessed using the QOLIE-10 (QOL in Epilepsy-10) instrument. Clinical and demographic characteristics were recorded, and instruments evaluating depressive/anxiety symptoms, sleep quality, and insomnia were completed. PWE had more depressive/anxiety symptoms when compared with controls. QOLIE-10 scores were significantly inversely correlated with poor sleep quality, insomnia symptoms, depressive/anxiety symptoms, and number of anti-epileptic drugs used, but not with seizure type or number of seizures per month. A poor QOL was independently associated only with anti-epileptic drug polytherapy. PWE are burdened with depressive/anxiety symptoms at alarming rates. The presence of depressive symptoms along with sleep disturbances and more significantly, anti-epileptic drug polytherapy, appears to negatively impact QOL, to a greater degree than short-term seizure control.