Details

Autor(en) / Beteiligte

• Bambini, F
• Santarelli, A
• Putignano, A
• Procaccini, M
• Orsini, G
• Di Iorio, D
• Memè, L
• Sartini, D
• Emanuelli, M
• Lo Muzio, L

Titel

Use of supercharged cover screw as static magnetic field generator for bone healing, 2nd part: in vivo enhancement of bone regeneration in rabbits

Ist Teil von

• Journal of biological regulators and homeostatic agents, 2017-04, Vol.31 (2), p.481-485

Ort / Verlag

Italy

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• In 1979, Pulsed electromagnetic fields (PEMFs) were approved by the Food and Drug Administration as an effective method in the treatment of non-unions. As well as PEMFs, also static magnetic fields (SMFs) have been widely investigated in orthopaedic studies. Even if the exact mechanism of action is not well understood, a large number of studies showed specific effects both at cellular and tissue levels. As bone fracture healing and osseointegration share the same biological events, the application of magnetic field stimulation in order to facilitate the osseointegration process has been suggested. In this study we investigated BIC and newly formed bone volume around dental implants inserted in the tibia of New Zealand rabbits after SMF stimulation, generated by a small-customized cover-screw-shaped neodymium-iron-bore magnet placed in the inner cavity of dental implants. As a result, we found that the SMF field generated around dental implants enhanced bone healing in the animal model. Our findings represent, to our knowledge, the first ready clinical technique for dental implants showing the ability of SMF to promote the osteogenesis process in vivo.