Details

Autor(en) / Beteiligte

• Schempp, Tabitha T
• Daniels, Blake E
• Staben, Steven T
• Stivala, Craig E

Titel

A General Strategy for the Construction of Functionalized Azaindolines via Domino Palladium-Catalyzed Heck Cyclization/Suzuki Coupling

Ist Teil von

• Organic letters, 2017-07, Vol.19 (13), p.3616-3619

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The preparation of substituted azaindolines utilizing a domino palladium-catalyzed Heck cyclization/Suzuki coupling is described. The approach is amenable for the construction of all four azaindoline isomers. A range of functional groups such as esters, amides, ketones, sulfones, amines, and nitriles are all tolerated under the reaction conditions.