Details

Autor(en) / Beteiligte

• Huang, Xiaoqiang
• Quinn, Taylor R
• Harms, Klaus
• Webster, Richard D
• Zhang, Lilu
• Wiest, Olaf
• Meggers, Eric

Titel

Direct Visible-Light-Excited Asymmetric Lewis Acid Catalysis of Intermolecular [2+2] Photocycloadditions

Ist Teil von

• Journal of the American Chemical Society, 2017-07, Vol.139 (27), p.9120-9123

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A reaction design is reported in which a substrate-bound chiral Lewis acid complex absorbs visible light and generates an excited state that directly reacts with a cosubstrate in a highly stereocontrolled fashion. Specifically, a chiral rhodium complex catalyzes visible-light-activated intermolecular [2+2] cycloadditions, providing a wide range of cyclobutanes with up to >99% ee and up to >20:1 d.r. Noteworthy is the ability to create vicinal all-carbon-quaternary stereocenters including spiro centers in an intermolecular fashion.