Details

Autor(en) / Beteiligte

• Fogazzi, G.B.
• Anderlini, R.
• Canovi, S.
• Covarelli, C.
• Gras, J.
• Kučera, J.
• Proietti, A.
• Rogic, D.
• Teboul, R.
• Ferraris Fusarini, C.
• de Liso, F.
• Garigali, G.
• Daudon, M.

Titel

“Daisy-like” crystals: A rare and unknown type of urinary crystal

Ist Teil von

• Clinica chimica acta, 2017-08, Vol.471, p.154-157

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• Crystals are well known structures of urinary sediment, most of which are identified by the combined knowledge of crystal morphology, birefringence features at polarized light, and urine pH. In this paper, we report on a cohort of subjects whose urine contained a very rare type of crystal, which we first described in 2004 and which, based on its peculiar morphology, we define as “daisy-like crystal” (DLcr). Reports on DLcr were spontaneously sent to our laboratory over a 10.5-year period by different laboratory professionals and by one veterinary clinician who, in their everyday work, had come across DLcr. After the examination of DLcr images submitted, a number of other information were requested and partly obtained. DLcr were found in 9 human beings in 7 different laboratories, located in 4 countries (Italy, Belgium, Croatia, France). DLcr were found mostly in female (8/9), at all ages (3.5 to 93years), mostly in alkaline urine (pH6.0 to 7.5), at variable specific gravity values (1.010 to 1.030), either as isolated particles (2/8) or in association with other crystals (5/8) and/or leucocytes or bacteria (3/8). In addition, DLcr were found in the urine of a 1-year-old dog, examined in a veterinary clinic of Czech Republic. In 3 cases, DLcr were identified by manual microscopy, while in 7 cases by automated urine sediment analyzers. This paper confirms the possible presence in the urine of DLcr. However, further cases are needed to clarify their frequency, clinical meaning, and composition. •The paper describes a very rare and almost unknown type of urinary crystal, which contains a peculiar type of carbonate.•Due to its particular morphology we define this crystal as “daily-like” crystal.•After our first description of this crystal in 2004, we report now on a cohort of 9 human beings +1 dog.•We also supply some clinical information about the subjects with this urinary crystals and the methods used to find it.•No other papers are present in the literature which describe this crystal.