Details

Autor(en) / Beteiligte

• Xiang, Jia-Chen
• Cheng, Yan
• Wang, Zi-Xuan
• Ma, Jin-Tian
• Wang, Miao
• Tang, Bo-Cheng
• Wu, Yan-Dong
• Wu, An-Xin

Titel

Oxidative Trimerization of Amino Acids: Selective Synthesis of 2,3,5-Trisubstituted Pyridines

Ist Teil von

• Organic letters, 2017-06, Vol.19 (11), p.2997-3000

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• An oxidative trimerization of three amino acids has been realized to furnish 2,3,5-trisubstuitued pyridines in both cross- and homo-trimerization types. This method is capable of converting simple linear biomass material to heterocycles, which features in the assembly of three amino acid branched chains into one aromatic ring. Molecular iodine triggers the sequential decarboxylation and deamination of amino acids and then promotes the selective formation of new C–N and C–C bonds.