Details

Autor(en) / Beteiligte

• Hyodo, Kengo
• Togashi, Kosuke
• Oishi, Naoki
• Hasegawa, Genna
• Uchida, Kingo

Titel

Brønsted Acid Catalyzed Nitrile Synthesis from Aldehydes Using Oximes via Transoximation at Ambient Temperature

Ist Teil von

• Organic letters, 2017-06, Vol.19 (11), p.3005-3008

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2017

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• The Brønsted acid-catalyzed synthesis of nitriles is described via transoximation under mild conditions using an O-protected oxime as a more stable equivalent of explosive O-protected hydroxylamines. The nitrile was generated via an O-protected aldoxime produced from the aldehyde and an O-protected oxime through transoximation. The reaction could be performed on a 1 g scale.