Details

Autor(en) / Beteiligte

• Kuramitsu, Shoichi, MD
• Jinnouchi, Hiroyuki, MD
• Shinozaki, Tomohiro, MPH
• Hiromasa, Takashi, MD
• Matsumura, Yukiko, MD
• Yamaji, Yuhei, MD
• Miura, Mizuki, MD
• Matsuda, Hiroaki, MD
• Masuda, Hisaki, MD
• Domei, Takenori, MD
• Soga, Yoshimitsu, MD, PhD
• Hyodo, Makoto, MD
• Shirai, Shinichi, MD
• Ando, Kenji, MD

Titel

Incidence and Long-Term Clinical Impact of Late-Acquired Stent Fracture After Sirolimus-Eluting Stent Implantation in Narrowed Coronary Arteries

Ist Teil von

• The American journal of cardiology, 2017-07, Vol.120 (1), p.55-62

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2017

Quelle

MEDLINE

Beschreibungen/Notizen

• The incidence and long-term clinical impact of stent fracture (SF) occurred beyond 1 year after sirolimus-eluting stent (SES) implantation remains unclear. From April 2004 to March 2008, 985 consecutive patients with 1,307 lesions were treated only with SES. Of these, 868 patients (88.1%) with 1,140 lesions underwent follow-up angiography within 1 year after the index procedure, and 646 patients (65.6%) with 872 lesions underwent it both within and beyond 1 year after the index procedure. According to the diagnosed timing of SF, we divided the patients into the 2 groups: early SF (<1 year after the index procedure) and late-acquired SF (>1 year after the index procedure). Early- and late-acquired SFs were observed in 64 of 868 patients (7.4%) and 66 of 1,140 lesions (5.8%); 12 of 646 patients (1.9%) and 12 of 872 lesions (1.4%), respectively. Cumulative 10-year incidence of clinically driven target lesion revascularization and definite stent thrombosis were numerically higher in the early- and late-acquired SF groups than in the non-SF group (41.6% vs 45.5% vs 19.0%; 8.0% vs 8.3% vs 2.0%, respectively). In conclusion, late-acquired SF after SES implantation occurred in 1.4% of lesions, which was lower than that of early SF. However, both early- and late-acquired SFs appeared to be associated with clinically driven target lesion revascularization and stent thrombosis during the long-term follow-up.